Emily E Brown Selected Research

Nicotinamide-Nucleotide Adenylyltransferase

1/2021	Mutant Nmnat1 leads to a retina-specific decrease of NAD+ accompanied by increased poly(ADP-ribose) in a mouse model of NMNAT1-associated retinal degeneration.
9/2020	Gene Therapy Preserves Retinal Structure and Function in a Mouse Model of NMNAT1-Associated Retinal Degeneration.

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Emily E Brown Research Topics

Disease

5	Retinal Degeneration 01/2022 - 01/2019
2	Disease Progression 01/2021 - 01/2019
2	Macular Degeneration (Age-Related Maculopathy) 01/2021 - 01/2019
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2021 - 01/2018
2	Dyslipidemias (Dyslipidemia) 01/2021 - 07/2020
2	Uveitis 12/2018 - 02/2016
2	Amyloidosis 09/2018 - 06/2017
1	Heart Failure 01/2019
1	Retinitis Pigmentosa (Pigmentary Retinopathy) 01/2019
1	Blindness (Hysterical Blindness) 01/2019
1	Herpes Zoster 12/2018
1	Carpal Tunnel Syndrome 09/2018
1	Congenital Heart Defects (Congenital Heart Defect) 04/2018
1	Cardiomyopathies (Cardiomyopathy) 04/2018

Drug/Important Bio-Agent (IBA)

3	Retinaldehyde (Retinal)IBA 01/2021 - 01/2019
2	Nicotinamide-Nucleotide AdenylyltransferaseIBA 01/2021 - 09/2020
2	Metformin (Glucophage)FDA LinkGeneric 01/2019 - 01/2019
2	Prealbumin (Transthyretin)IBA 09/2018 - 06/2017
2	Amyloid (Amyloid Fibrils)IBA 09/2018 - 06/2017
1	EnzymesIBA 01/2022
1	Adenine FDA LinkGeneric 01/2021
1	Histones (Histone)IBA 01/2021
1	SirtuinsIBA 01/2021
1	NAD (NADH)IBA 01/2021
1	Niacinamide (Nicotinamide)FDA LinkGeneric 01/2021
1	Poly Adenosine Diphosphate RiboseIBA 01/2021
1	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 10/2020
1	LipidsIBA 07/2020
1	Biological ProductsIBA 07/2020
1	DNA (Deoxyribonucleic Acid)IBA 07/2020
1	Protein Kinases (Protein Kinase)IBA 01/2019
1	Hypoglycemic Agents (Hypoglycemics)IBA 01/2019
1	Adenosine Monophosphate (AMP)IBA 01/2019
1	sodium iodateIBA 01/2019
1	OccludinIBA 12/2018
1	Interleukin-17 (Interleukin 17)IBA 12/2018
1	Tight Junction ProteinsIBA 12/2018
1	Cell-Penetrating PeptidesIBA 12/2018
1	Proteins (Proteins, Gene)FDA Link 04/2018
1	Peptides (Polypeptides)IBA 06/2017
1	Interleukin-6 (Interleukin 6)IBA 02/2016
1	EndotoxinsIBA 02/2016

Therapy/Procedure

3	Therapeutics 01/2019 - 06/2017
1	Precision Medicine 01/2021
1	Heart-Assist Devices 01/2019
1	Liver Transplantation 06/2017
1	Intravitreal Injections 02/2016